A team of University of Vermont (UVM), Case Western Reserve University (CWRU), and Portland Oregon Health & Sciences University (OHSU) / Portland VA Medical Center (PVAMC) has received a competitive $400,000, two-year grant starting September 2021 from the Department of Defense (DOD) to develop and Ontology-based, Real-time, Machine learning Informatics System for Parkinson’s Disease (ORMIS-PD).
US DOD Award Number: W81XWH-21-1-0859

Principal investigator Deepak K. Gupta, MD, Assistant Professor of Neurological Sciences at LCOM, will lead this collaborative, multi-site project. Dr. Gupta and his team will first develop ORMIS-PD through integration of Parkinson & Movement Disorders Ontology (PMDO)-based clinical data capture at point-of-care and machine learning algorithm with the Movement Disorders Society (MDS) clinical diagnostic criteria for PD (MDS-PD criteria) criteria and Parkinson Progression Marker Initiative (PPMI) data. Then, ORMIS-PD will be implemented to compare differences in ORMIS-PD generated diagnostic classification and prognosis measures between neurotoxin-associated PD and idiopathic PD at the University of Vermont Medical Center (UVMMC) and OHSU/PVAMC.
In addition to Dr. Gupta, team investigators include James Boyd, MD, Professor of Neurological Sciences at UVM; Satya S. Sahoo, PhD, Associate Professor of Computer Science and Director of Biomedical Health Informatics PhD program at CWRU; and Amie Hiller, MD, Associate Professor of Neurology at OHSU/PVAMC. Other members of team include Katherine Chan, Research Coordinator in department of neurology at UVMMC, Ms. Katrina Prantzalos, Postdoctoral Graduate Student at CWRU, Ms. Brenna Lobb, Research Coordinator at OHSU/PVAMC.
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